Article
Association analysis between SNPs in IL-28B gene and the progress of hepatitis B infection in Han Chinese.
PloS one - 1 Jan 2012
Chen Jie, Wang Lanlan, Li Yi, Cai Bei, Fu Yang, Liao Yun, Zhang Junlong
Abstract excerpt
OBJECTIVE: As a candidate gene association study, we investigated the genetic association of SNPs in IL-28B genes with different outcomes of HBV infection, including LC and HCC occurrence. METHODS: Chinese Han subjects were categorized into two groups: 406 LC caused by CHB and 406 HCC caused by CHB. Genomic DNA was isolated from whole blood samples, SNPs were detected using high resolution melting curve (HRM)...
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