Article
Thymic stromal lymphopoietin: an immune cytokine gene associated with the metabolic syndrome and blood pressure in severe obesity.
Clinical science (London, England : 1979) - 1 Jul 2012
Turcot Valérie, Bouchard Luigi, Faucher Geneviève, Garneau Véronique, Tchernof André, Deshaies Yves, Pérusse Louis, Marceau Simon, Biron Simon, Lescelleur Odette, Biertho Laurent, Vohl Marie-Claude
Abstract excerpt
A previous expression profiling of VAT (visceral adipose tissue) revealed that the TSLP (thymic stromal lymphopoietin) gene was less expressed in severely obese men with (n=7) compared with without (n=7) the MetS (metabolic syndrome). We hypothesized that TSLP SNPs (single nucleotide polymorphisms) are associated with TSLP gene expression in VAT and with MetS phenotypes. Following validation of lower TSLP...
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