Article
Association of IL-10 gene (-1082A>G, -819C>T and -592C>A) polymorphism and its serum level with metabolic syndrome of north Indian subjects.
Journal of genetics - 1 Mar 2017
Madeshiya Amit Kumar, Singh Shraddha, Dwivedi Shipra, Konwar Rituraj, Natu Shankar Madhav, Ghatak Ashim
Abstract excerpt
Metabolic syndrome (MetS) is an inflammatory disorder, in which various cytokines play important role in tilting balance towards disease state. Interleukin-10 (IL-10) is an important antiinflammatory cytokine, but its genetic polymorphisms and serum levels in Indian MetS subjects are unknown. Three IL-10 gene polymorphisms (-1082A>G (rs1800896), -819C>T (rs1800872) and -592C>A (rs1800871)) were genotyped with...
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