Article
A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups.
Journal of human genetics - 1 May 2009
Parathyras John, Gebhardt Stefan, Hillermann-Rebello Renate, Grobbelaar Nelis, Venter Mauritz, Warnich Louise
Abstract excerpt
South Africa, like many other Southern African countries, has one of the highest HIV infection rates in the world and many individuals consequently receive antiretroviral therapy (ART). However, knowledge regarding (i) the prevalence of functional single nucleotide polymorphisms (SNPs) in pharmacologically relevant genes, and (ii) variance in pharmacotherapy both within and between different populations and...
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