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Article

Association of COL25A1 with comorbid antisocial personality disorder and substance dependence.

Biological psychiatry - 15 Apr 2012

Li Dawei, Zhao Hongyu, Kranzler Henry R, Oslin David, Anton Raymond F, Farrer Lindsay A, Gelernter Joel

Abstract excerpt

BACKGROUND: Antisocial personality disorder (ASPD) is a psychiatric disorder characterized by a long-term pattern of manipulating, exploiting, or violating the rights of others. METHODS: Subjects ascertained for genetic studies of substance dependence (SD) and diagnosed with ASPD and comorbid SD were included in a two-stage genetic association study. In the discovery stage, 627 single nucleotide polymorphisms...

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Identifiers

PMID: 22297151
DOI: 10.1016/j.biopsych.2011.12.011
PMCID: PMC3548659

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