Article
[Genome-wide association study of bronchial asthma in the Volga-Ural region of Russia].
Molekuliarnaia biologiia - 1 Jan 2000
Karunas A S, Iunusbaev B B, Fedorova Iu Iu, Gimalova G F, Ramazanova N N, Gur'eva L L, Mukhtarova L A, Zagidullin Sh Z, Etkina E I, Khusnutdinova E K
Abstract excerpt
Bronchial asthma is a chronic inflammatory respiratory disease that is caused by the complex interaction of environmental influences and genetic susceptibility. The first genome-wide association study of bronchial asthma discovered a significant association between SNPs within 17q12-21 genomic region and childhood bronchial asthma in individuals of European descent. Association with this genomic region was then...
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