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Article

Increased intratumoral neutrophil in colorectal carcinomas correlates closely with malignant phenotype and predicts patients' adverse prognosis.

PloS one - 1 Jan 2012

Rao Hui-Lan, Chen Jie-Wei, Li Mei, Xiao Yong-Bo, Fu Jia, Zeng Yi-Xin, Cai Mu-Yan, Xie Dan

Abstract excerpt

BACKGROUND: Substantial evidence suggests that the presence of inflammatory cells plays a critical role in the development and/or progression of human tumors. Neutrophils are the common inflammatory cells in tumors; however, the infiltration of intratumoral neutrophils in colorectal carcinoma (CRC) and its effect on CRC patients' prognosis are poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: In this study, the...

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Identifiers

PMID: 22295111
DOI: 10.1371/journal.pone.0030806
PMCID: PMC3266280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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