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Article

Granulocyte-Macrophage Colony-Stimulating Factor-Activated Neutrophils Express B7-H4 That Correlates with Gastric Cancer Progression and Poor Patient Survival.

Journal of immunology research - 1 Jan 2021

Shan Zhi-Guo, Yan Zong-Bao, Peng Liu-Sheng, Cheng Ping, Teng Yong-Sheng, Mao Fang-Yuan, Fan Kun, Zhuang Yuan, Zhao Yong-Liang

Abstract excerpt

Neutrophils are prominent components of gastric cancer (GC) tumors and exhibit distinct phenotypes in GC environment. However, the phenotype, regulation, and clinical relevance of neutrophils in human GC are presently unknown. Here, immunohistochemistry, real-time PCR, and flow cytometry analyses were performed to examine levels and phenotype of neutrophils in samples from 41 patients with GC, and also isolated,...

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Identifiers

PMID: 33763491
DOI: 10.1155/2021/6613247
PMCID: PMC7962878

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