Article
Microevolution of extensively drug-resistant tuberculosis in Russia.
Genome research - 1 Apr 2012
Casali Nicola, Nikolayevskyy Vladyslav, Balabanova Yanina, Ignatyeva Olga, Kontsevaya Irina, Harris Simon R, Bentley Stephen D, Parkhill Julian, Nejentsev Sergey, Hoffner Sven E, Horstmann Rolf D, Brown Timothy, Drobniewski Francis
Abstract excerpt
Extensively drug-resistant (XDR) tuberculosis (TB), which is resistant to both first- and second-line antibiotics, is an escalating problem, particularly in the Russian Federation. Molecular fingerprinting of 2348 Mycobacterium tuberculosis isolates collected in Samara Oblast, Russia, revealed that 72% belonged to the Beijing lineage, a genotype associated with enhanced acquisition of drug resistance and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
