Article
Whole-Genome Sequencing of Mycobacterium tuberculosis Provides Insight into the Evolution and Genetic Composition of Drug-Resistant Tuberculosis in Belarus.
Journal of clinical microbiology - 1 Feb 2017
Wollenberg Kurt R, Desjardins Christopher A, Zalutskaya Aksana, Slodovnikova Vervara, Oler Andrew J, Quiñones Mariam, Abeel Thomas, Chapman Sinead B, Tartakovsky Michael, Gabrielian Andrei, Hoffner Sven, Skrahin Aliaksandr, Birren Bruce W, Rosenthal Alexander, Skrahina Alena, Earl Ashlee M
Abstract excerpt
The emergence and spread of drug-resistant Mycobacterium tuberculosis (DR-TB) are critical global health issues. Eastern Europe has some of the highest incidences of DR-TB, particularly multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB. To better understand the genetic composition and evolution of MDR- and XDR-TB in the region, we sequenced and analyzed the genomes of 138 M. tuberculosis isolates...
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