Article
Insight into Population Structure and Drug Resistance of Pediatric Tuberculosis Strains from China and Russia Gained through Whole-Genome Sequencing.
International journal of molecular sciences - 18 Jun 2023
Zhdanova Svetlana, Jiao Wei-Wei, Sinkov Viacheslav, Khromova Polina, Solovieva Natalia, Mushkin Alexander, Mokrousov Igor, Belopolskaya Olesya, Masharsky Aleksey, Vyazovaya Anna, Rychkova Lubov, Kolesnikova Lubov, Zhuravlev Viacheslav, Shen A-Dong, Ogarkov Oleg
Abstract excerpt
This study aimed to determine phenotypic and genotypic drug resistance patterns of Mycobacterium tuberculosis strains from children with tuberculosis (TB) in China and Russia, two high-burden countries for multi/extensively-drug resistant (MDR/XDR) TB. Whole-genome sequencing data of M. tuberculosis isolates from China (n = 137) and Russia (n = 60) were analyzed for phylogenetic markers and drug-resistance...
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