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Article

Next-Generation Sequencing for Characterizing Drug Resistance-Conferring Mycobacterium tuberculosis Genes from Clinical Isolates in the Ukraine.

Journal of clinical microbiology - 1 Jun 2018

Daum L T, Konstantynovska O S, Solodiankin O S, Liashenko O O, Poteiko P I, Bolotin V I, Hrek I I, Rohozhyn A V, Rodriguez J D, Fischer G W, Chambers J P, Gerilovych A P

Abstract excerpt

The Ukraine ranks among the top 20 countries with the highest number of multidrug-resistant (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis cases in the world. However, little is known of the genetic diversity, i.e., resistance signatures, in clinical isolates from this region. We analyzed seven of most prevalent MDR/XDR antibiotic resistance-conferring genes from clinical isolates (n = 75)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29563202
DOI: 10.1128/JCM.00009-18
PMCID: PMC5971536

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