Article
Up-regulation of human arrest-defective 1 protein is correlated with metastatic phenotype and poor prognosis in breast cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Wang Ze-Hua, Gong Jun-Li, Yu M, Yang H, Lai J H, Ma M X, Wu H, Li L, Tan D Y
Abstract excerpt
BACKGROUND: Human arrest defective 1 protein (ARD1), as a N-terminal acetyltransferase, has been reported to play a crucial role in tumorigenesis, but the results are somewhat controversial. To explore the clinical and pathological significance of ARD1 in breast tumorigenesis, we analyzed ARD1 status in multiple types of breast disease. METHODS: The expression of ARD1 protein was assessed by immunohistochemistry...
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