Article
Association between variations in cell cycle genes and idiopathic pulmonary fibrosis.
PloS one - 1 Jan 2012
Korthagen Nicoline M, van Moorsel Coline H M, Barlo Nicole P, Kazemier Karin M, Ruven Henk J T, Grutters Jan C
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a devastating and progressive lung disease. Its aetiology is thought to involve damage to the epithelium and abnormal repair. Alveolar epithelial cells near areas of remodelling show an increased expression of proapoptotic molecules. Therefore, we investigated the role of genes involved in cell cycle control in IPF. Genotypes for five single nucleotide polymorphisms (SNPs)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.