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Clinical applications of patient-specific induced pluripotent stem cells in cardiovascular medicine

27 Jan 2012

Abstract excerpt

The emergence of induced pluripotent stem cell (iPSC) technology has had a great impact on the field of medicine ever since the ground-breaking discovery in 2006 that overexpression of four specific transcription factors was able to turn back the developmental clock of somatic cells into an embryonic-like state. The resulting iPSCs carry the developmental potential of human embryonic stem cells (hESC) without the...

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PMID: 22285968
DOI: 10.1136/heartjnl-2011-301317

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