Molecular Markers Increase Precision of the European Association of Urology Non-Muscle-Invasive Bladder Cancer Progression Risk Groups.

doi:10.1158/1078-0432.CCR-17-2719

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Article

Molecular Markers Increase Precision of the European Association of Urology Non-Muscle-Invasive Bladder Cancer Progression Risk Groups.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2018

van Kessel Kim E M, van der Keur Kirstin A, Dyrskjøt Lars, Algaba Ferran, Welvaart Naeromy Y C, Beukers Willemien, Segersten Ulrika, Keck Bastian, Maurer Tobias, Simic Tatjana, Horstmann Marcus, Grimm Marc-Oliver, Hermann Gregers G, Mogensen Karin, Hartmann Arndt, Harving Niels, Petersen Astrid C, Jensen Jørgen B, Junker Kerstin, Boormans Joost L, Real Francisco X, Malats Núria, Malmström Per-Uno, Ørntoft Torben F, Zwarthoff Ellen C

Abstract excerpt

Purpose: The European Association of Urology (EAU) guidelines for non-muscle-invasive bladder cancer (NMIBC) recommend risk stratification based on clinicopathologic parameters. Our aim was to investigate the added value of biomarkers to improve risk stratification of NMIBC.Experimental Design: We prospectively included 1,239 patients in follow-up for NMIBC in six European countries. Fresh-frozen tumor samples...

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Identifiers

PMID: 29367430
DOI: 10.1158/1078-0432.CCR-17-2719

Genes

PIR
FGFR3
GATA2
TBX3
TBX2
TERT
ZIC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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