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Article

Association between HLA class II alleles and hepatitis B virus infection in Transylvania, Romania.

Immunological investigations - 1 Oct 2018

Matei Horea Vladi, Vica Mihaela Laura, Siserman Costel Vasile

Abstract excerpt

Infection with hepatitis B virus (HBV) is a major problem worldwide. The major histocompatibility complex plays an essential role in host immunity and can help eliminate the HBV of infected hepatocytes. Our study aimed to determine the role of certain human leukocyte antigen (HLA) class II molecules (i.e. HLA-DRB1 and HLA-DQB1) in the persistence or removal of HBV. Sixty patients confirmed to be HBV-positive via...

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PMID: 29979894
DOI: 10.1080/08820139.2018.1489832

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