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Article

Derivation of human embryonic stem cells with NEMO deficiency.

Stem cell research - 1 May 2012

Guan Xiao, Yabuuchi Akiko, Huo Hongguang, Ginsberg Elizabeth, Racowsky Catherine, Daley George Q, Lerou Paul H

Abstract excerpt

Deficiency of the nuclear factor-kappa-B essential modulator (NEMO) is a rare X-linked disorder that presents in boys as hypohydrotic ectodermal dysplasia with immunodeficiency due to defective nuclear factor-κB activation. Here we report on the generation of 2 human embryonic stem cell lines from discarded in vitro fertilization (IVF) embryos ascertained via preimplantation genetic diagnosis. We have derived two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22284529
DOI: 10.1016/j.scr.2011.12.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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