Article
Caveolin-1 expression predicts favourable outcome and correlates with PDGFRA mutations in gastrointestinal stromal tumours (GISTs).
Journal of clinical pathology - 1 Dec 2022
Bertero Luca, Gambella Alessandro, Barreca Antonella, Osella-Abate Simona, Chiusa Luigi, Francia di Celle Paola, Lista Patrizia, Papotti Mauro, Cassoni Paola
Abstract excerpt
AIMS: Novel prognostic markers are warranted for gastrointestinal stromal tumours. Caveolin-1 is a multifunctional protein that proved to be associated with outcome in multiple tumour types. Aim of this study was to investigate Caveolin-1 expression and prognostic efficacy in a series of gastrointestinal stromal tumours. METHODS: Caveolin-1 expression was assessed by immunohistochemistry in a retrospective series...
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