Article
Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction.
Blood - 15 Mar 2012
Hasegawa Atsushi, Shimizu Ritsuko, Mohandas Narla, Yamamoto Masayuki
Abstract excerpt
GATA1 plays essential roles in erythroid gene expression. The N-terminal finger of GATA1 (GATA1-Nf) is important for association with FOG1. Substitution mutations in GATA1-Nf, such as GATA1(V205M) that diminish the GATA1-FOG1 association, have been identified in human thrombocytopenia and anemia...
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