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Article

The association between ATM IVS 22-77 T>C and cancer risk: a meta-analysis.

PloS one - 1 Jan 2012

Zhao Lin, Gu Aihua, Ji Guixiang, Zou Peng, Zhao Peng, Lu Ailin

Abstract excerpt

BACKGROUND AND OBJECTIVES: It has become increasingly clear that ATM (ataxia-telangiectasia-mutated) safeguards genome stability, which is a cornerstone of cellular homeostasis, and ATM IVS 22-77 T>C affects the normal activity of ATM proteins. However, the association between the ATM IVS 22-77 T>C genetic variant and cancer risk is controversial. Therefore, we conducted a systematic meta-analysis to estimate the...

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Source

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Identifiers

PMID: 22276117
DOI: 10.1371/journal.pone.0029479
PMCID: PMC3261868

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The association between ATM IVS 22-77 T>C and cancer risk: a meta-analysis.PMID 22276117Read ↗

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