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Nitroglycerin prevents coagulopathies and foetal death associated with abnormal maternal inflammation in rats.

Thrombosis and haemostasis - 1 May 2012

Cotechini Tiziana, Othman Maha, Graham Charles H

Abstract excerpt

Inflammation-associated foetal loss is often linked to maternal coagulopathies. Here, we characterised the role of maternal inflammation in the development of various systemic maternal coagulopathies and foetal death during mid-to-late gestation in rats. Since nitric oxide (NO) functions as an inhibitor of platelet aggregation and anti-oxidant, we also tested whether the NO mimetic nitroglycerin (glyceryl...

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PMID: 22274747
DOI: 10.1160/TH11-10-0730

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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