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Article

Unexplained fetal death: Another anti-angiogenic state

1 Jan 2007

Abstract excerpt

BACKGROUND: Pregnancy creates a unique situation in which both vasculogenesis and extensive angiogenesis are required for successful fetal and placental development. Recently, the soluble form of vascular endothelial growth factor (VEGF) receptor-1 (sVEGFR-1), an antagonist to VEGF and placental growth factor (PlGF) (two important angiogenic factors), has been implicated in the pathophysiology of preeclampsia and...

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PMID: 17674262
DOI: 10.1080/14767050701413022

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