Article
Maternal plasma proteomics in a rat model of pregnancy complications reveals immune and pro-coagulant gene pathway activation.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Feb 2020
Sanchez Tino W, Li Bo, Molinaro Christine, Casiano Carlos A, Bellinger Denise L, Mata-Greenwood Eugenia
Abstract excerpt
PROBLEM: The Brown Norway (BN) rat is a model of T-helper 2 immune diseases, and also a model of pregnancy disorders that include placental insufficiency, fetal loss, and pre-eclampsia-like symptoms. The aim of this study was to investigate the plasma proteomic/cytokine profile of pregnant BN rats in comparison to that of the Lewis (LEW) rat strain. METHOD OF STUDY: Plasma proteomics differences were studied at...
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