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Targeting Neutrophil Extracellular Trap Formation: Exploring Promising Pharmacological Strategies for the Treatment of Preeclampsia

9 May 2024

Abstract excerpt

Neutrophils, which constitute the most abundant leukocytes in human blood, emerge as crucial players in the induction of endothelial cell death and the modulation of endothelial cell responses under both physiological and pathological conditions. The hallmark of preeclampsia is endothelial dysfunction induced by systemic inflammation, in which neutrophils, particularly through the formation of neutrophil...

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Share to Inflammation biomarkers and pathways
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Nitric Oxide and Endothelin Effects

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PMID: 38794175
DOI: 10.3390/ph17050605

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