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Article

The genetic origin and history of speed in the Thoroughbred racehorse.

Nature communications - 24 Jan 2012

Bower Mim A, McGivney Beatrice A, Campana Michael G, Gu Jingjing, Andersson Lisa S, Barrett Elizabeth, Davis Catherine R, Mikko Sofia, Stock Frauke, Voronkova Valery, Bradley Daniel G, Fahey Alan G, Lindgren Gabriella, MacHugh David E, Sulimova Galina, Hill Emmeline W

Abstract excerpt

Selective breeding for speed in the racehorse has resulted in an unusually high frequency of the C-variant (g.66493737C/T) at the myostatin gene (MSTN) in cohorts of the Thoroughbred horse population that are best suited to sprint racing. Here we show using a combination of molecular- and pedigree-based approaches in 593 horses from 22 Eurasian and North-American horse populations, museum specimens from 12...

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PMID: 22273681
DOI: 10.1038/ncomms1644

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MSTN

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