Article
Role of tumor necrosis factor gene single nucleotide polymorphisms in the natural course of 2009 influenza A H1N1 virus infection.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2012
Antonopoulou Anastasia, Baziaka Fotini, Tsaganos Thomas, Raftogiannis Maria, Koutoukas Pantelis, Spyridaki Aikaterini, Mouktaroudi Maria, Kotsaki Antigone, Savva Athina, Georgitsi Marianna, Giamarellos-Bourboulis Evangelos J
Abstract excerpt
OBJECTIVES: To identify the role of single nucleotide polymorphisms (SNPs) of the tumor necrosis factor (TNF) gene in the natural course of 2009 influenza A H1N1 virus infection. METHODS: Genomic DNA was isolated from 109 patients with an H1N1 infection and from 108 healthy volunteers. SNPs of the TNF gene were assessed after electrophoresis of the digested PCR products by restriction enzymes. RESULTS: The...
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