Article
Functionalised cyclopentadienyl titanium compounds as potential anticancer drugs
1 Jan 2007
Abstract excerpt
A number of new ionic titanocene compounds have been isolated and characterised, which exhibit excellent cytotoxicity against different human tumour cell lines including a defined cisplatin resistant cell line. A range of biological assays have been carried out to determine levels of cytotoxicity and levels of DNA interstrand crosslinking.
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