Article
[Mutation of ING1 gene in laryngeal squamous cell carcinoma and its association with p33ING1b protein expression].
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery - 1 Nov 2011
Li Fengying, Li Jun, Sheng Hongqiang, Dai Libo, Cheng Kejia, Lin Shan
Abstract excerpt
OBJECTIVE: To investigate the ING1 gene mutation status in human laryngeal squamous cell carcinoma(LSCC), and the association of p33(ING1b) protein expression with p53 protein expression. METHOD: DNA of LSCC tissue was extracted, and nucleotide of the second exon was amplified and sequenced to determine the chromosome status. The p23(ING1b) and p53 protein expression were detected by immunohistochemistry and the...
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