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Article

Variations in CRHR1 are associated with persistent pulmonary hypertension of the newborn.

Pediatric research - 1 Feb 2012

Byers Heather M, Dagle John M, Klein Jonathan M, Ryckman Kelli K, McDonald Erin L, Murray Jeffrey C, Borowski Kristi S

Abstract excerpt

INTRODUCTION: Persistent pulmonary hypertension of the newborn (PPHN) is associated with substantial infant morbidity and mortality. Recently, genetic associations have been found in idiopathic pulmonary arterial hypertension. RESULTS: PPHN was significantly (P < 0.05) associated with genetic variants in corticotropin-releasing hormone (CRH) receptor 1, CRHR1 and CRH-binding protein, CRHBP. Association with CRHR1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22258127
DOI: 10.1038/pr.2011.24
PMCID: PMC3718388

Genes

CRHR1
BMPR2
CRH
CRHBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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