Article
Variation in the maternal corticotrophin releasing hormone-binding protein (CRH-BP) gene and birth weight in Blacks, Hispanics and Whites.
PloS one - 1 Jan 2012
Wadhwa Pathik D, Simhan Hyagriv N, Entringer Sonja, Buss Claudia, Smith Roger, Hobel Calvin J, Farhana Naveed, Shimmin Lawrence, Hixson James E, Sing Charles F
Abstract excerpt
BACKGROUND: Given the unique role of the corticotrophin-releasing hormone (CRH) system in human fetal development, the aim of our study was to estimate the association of birth weight with DNA sequence variation in three maternal genes involved in regulating CRH production, bioavailability and action: CRH, CRH-Binding Protein (CRH-BP), and CRH type 1 receptor (CRH-R1), respectively, in three racial groups...
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