Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b

12 Jan 2012

Abstract excerpt

BACKGROUND: The causative agent of severe acute respiratory syndrome, SARS coronavirus (SARS-CoV) genome encodes several unique group specific accessory proteins with unknown functions. Among them, accessory protein 3b (also known as ORF4) was lately identified as one of the viral interferon antagonist. Recently our lab uncovered a new role for 3b in upregulation of AP-1 transcriptional activity and its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22253733
DOI: 10.1371/journal.pone.0029542

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1bPMID 22253733Read ↗

SARS-CoV Accessory Protein 3b Induces AP-1 Transcriptional Activity through Activation of JNK and ERK PathwaysSemantic proximity Read ↗

The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunitySemantic proximity Read ↗

The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunitySemantic proximity Read ↗

Middle East Respiratory Syndrome Coronavirus Accessory Protein 4a Is a Type I Interferon AntagonistSemantic proximity Read ↗

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infectionSemantic proximity Read ↗

Bat severe acute respiratory syndrome-like coronavirus ORF3b homologues display different interferon antagonist activitiesSemantic proximity Read ↗

Kaposi's Sarcoma-associated Herpesvirus-encoded vIRF-3 Stimulates the Transcriptional Activity of Cellular IRF-3 and IRF-7Semantic proximity Read ↗

Middle East Respiratory Syndrome Coronavirus-Encoded Accessory Proteins Impair MDA5-and TBK1-Mediated Activation of NF-��BSemantic proximity Read ↗

SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interactionSemantic proximity Read ↗

A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication.Semantic proximity Read ↗

Evidence for BAG3 modulation of HIV-1 gene transcription.Semantic proximity Read ↗

The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.