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Alkaline and neutral Comet assay profiles of sperm DNA damage in clinical groups

16 Jan 2012

Abstract excerpt

BACKGROUND: The analysis of sperm DNA fragmentation has become a new marker to predict male infertility, and many techniques have been developed. The sperm Comet assay offers the possibility of differentiating single- and double-stranded DNA (ssDNA and dsDNA) breaks, which could have different effects on fertility. The objective of this study was to perform a descriptive characterization of different groups of...

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PMID: 22252081
DOI: 10.1093/humrep/der461

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