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Human semen cryopreservation: a sperm DNA fragmentation study with alkaline and neutral Comet assay

20 Nov 2013

Abstract excerpt

Sperm cryopreservation is widely used for both research and reproduction purposes, but its effect on sperm DNA damage remains controversial. Sperm DNA fragmentation (SDF) has become an important biomarker to assess male infertility. In particular, the differentiation between single- and double-stranded DNA fragmentation (ssSDF and dsSDF) has clinical implications for male infertility where ssSDF is associated...

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PMID: 24255006
DOI: 10.1111/j.2047-2927.2013.00158.x

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