Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DNA damage response in viral-induced cellular transformation

1 Jan 2012

Abstract excerpt

The DNA damage response (DDR) has emerged as a critical tumour suppressor pathway responding to cellular DNA replicative stress downstream of aberrant oncogene over-expression. Recent studies have now implicated the DDR as a sensor of oncogenic virus infection. In this review, we discuss the mechanisms by which tumour viruses activate and also suppress the host DDR. The mechanism of tumour virus induction of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Polyomavirus and related diseases
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22240795
DOI: 10.1038/bjc.2011.612

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DNA damage response in viral-induced cellular transformationPMID 22240795Read ↗

Modulation of DNA Damage and Repair Pathways by Human Tumour VirusesSemantic proximity Read ↗

Viruses and the DNA Damage Response: Activation and AntagonismSemantic proximity Read ↗

Interplay between the DNA damage response and the life cycle of DNA tumor virusesSemantic proximity Read ↗

At a Crossroads: Human DNA Tumor Viruses and the Host DNA Damage ResponseSemantic proximity Read ↗

Take your PIKK: tumour viruses and DNA damage response pathwaysSemantic proximity Read ↗

Viral-induced human carcinogenesis: an oxidative stress perspectiveSemantic proximity Read ↗

Activation of the DNA Damage Response by RNA VirusesSemantic proximity Read ↗

The DNA Damage Response Induced by Infection with Human Cytomegalovirus and Other VirusesSemantic proximity Read ↗

DNA viruses and the cellular DNA-damage responseSemantic proximity Read ↗

The Role of the DNA Damage Response throughout the Papillomavirus Life CycleSemantic proximity Read ↗

Virus DNA Replication and the Host DNA Damage ResponseSemantic proximity Read ↗

Viruses and Human Cancers: a Long Road of Discovery of Molecular ParadigmsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.