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Article

Prenatal immune activation interacts with genetic Nurr1 deficiency in the development of attentional impairments.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Jan 2012

Vuillermot Stéphanie, Joodmardi Eliza, Perlmann Thomas, Ögren Sven Ove, Feldon Joram, Meyer Urs

Abstract excerpt

Prenatal exposure to infection has been linked to increased risk of neurodevelopmental brain disorders, and recent evidence implicates altered dopaminergic development in this association. However, since the relative risk size of prenatal infection appears relatively small with respect to long-term neuropsychiatric outcomes, it is likely that this prenatal insult interacts with other factors in shaping the risk...

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Identifiers

PMID: 22238080
DOI: 10.1523/JNEUROSCI.4831-11.2012
PMCID: PMC6621065

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