Weight-loss diets modify glucose-dependent insulinotropic polypeptide receptor rs2287019 genotype effects on changes in body weight, fasting glucose, and insulin resistance: the Preventing Overweight Using Novel Dietary Strategies trial.

doi:10.3945/ajcn.111.025270

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Article

Weight-loss diets modify glucose-dependent insulinotropic polypeptide receptor rs2287019 genotype effects on changes in body weight, fasting glucose, and insulin resistance: the Preventing Overweight Using Novel Dietary Strategies trial.

The American journal of clinical nutrition - 1 Feb 2012

Qi Qibin, Bray George A, Hu Frank B, Sacks Frank M, Qi Lu

Abstract excerpt

BACKGROUND: Glucose-dependent insulinotropic polypeptide [also known as gastric inhibitory polypeptide (GIP)] and its receptor (GIPR) may link overnutrition to obesity, insulin resistance, and type 2 diabetes. A GIPR variant rs2287019 was recently associated with obesity and glucose metabolism. OBJECTIVE: We aimed to examine whether weight-loss diets that vary in fat content may modify the effect of this variant...

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Identifiers

PMID: 22237064
DOI: 10.3945/ajcn.111.025270
PMCID: PMC3260076

Genes

GIPR
GIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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