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Article

Amniotic fluid stem cell-based models to study the effects of gene mutations and toxicants on male germ cell formation.

Asian journal of andrology - 1 Mar 2012

Gundacker Claudia, Dolznig Helmut, Mikula Mario, Rosner Margit, Brandau Oliver, Hengstschläger Markus

Abstract excerpt

Male infertility is a major public health issue predominantly caused by defects in germ cell development. In the past, studies on the genetic regulation of spermatogenesis as well as on negative environmental impacts have been hampered by the fact that human germ cell development is intractable to direct analysis in vivo. Compared with model organisms including mice, there are fundamental differences in the...

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Identifiers

PMID: 22231297
DOI: 10.1038/aja.2011.170
PMCID: PMC3735087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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