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Human Amniotic Fluid Stem Cells Possess the Potential to Differentiate into Primordial Follicle Oocytes In Vitro1

27 Feb 2014

Abstract excerpt

Previous reports have demonstrated that embryonic stem cells were capable of differentiating into primordial germ cells through the formation of embryoid bodies that subsequently generated oocyte-like cells (OLCs). Such a process could facilitate studies of primordial follicle oocyte development in vitro and regenerative medicine. To investigate the pluripotency of human amniotic fluid stem cells (hAFSCs) and...

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PMID: 24571984
DOI: 10.1095/biolreprod.113.112920

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