Article
Virus C genotype predisposes to primary hypothyroidism during interferon-α treatment for chronic hepatitis C.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Pavan Maria Helena Postal, Pavin Elizabeth João, Gonçales Fernando Lopes, Zantut-Wittmann Denise E, Wittmann Denise Engelbrecht Zantut
Abstract excerpt
OBJECTIVE: The treatment of the chronic hepatitis C (HCV) with α-interferon is associated with thyroid dysfunction (TD). The aim of this study was to evaluate thyroid function outcome among patients with chronic HCV under treatment with conventional interferon (IFN) or peguilated interferon (PEG-IFN) in association with ribavirin. PATIENTS AND METHODS: We studied 293 patients with chronic HCV, submitted to drug...
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