Article
Interferon alpha treatment and thyroid dysfunction.
Endocrinology and metabolism clinics of North America - 1 Dec 2007
Tomer Yaron, Blackard Jason T, Akeno Nagako
Abstract excerpt
Interferon alpha (IFN alpha) is the cornerstone therapeutic agent for chronic hepatitis C virus (HCV) infection. Prospective studies have shown that up to 15% of HCV patients receiving IFN alpha develop clinical thyroid disease, and up to 40% become thyroid antibody positive. In some cases IFN-induced thyroiditis (IIT) may result in discontinuation of interferon therapy; thus, IIT represents a major clinical...
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