Article
Association between human leukocyte antigen (HLA) and interferon- induced thyroid diseases in four patients with HCV-related chronic hepatitis.
Neuro endocrinology letters - 1 Apr 2005
Labbadia Giancarlo, Martocchia Antonio, Mammarella Antonio, Paoletti Vincenzo, Rocco Antonio, Benvenuto Rosalba, Antonella Proietti, Rosaria D'Urso, Trabace Simonetta, Musca Antonino, Falaschi Paolo
Abstract excerpt
OBJECTIVES: The interferon-alpha (IFN-alpha) therapy for HCV hepatitis may exacerbate or induce underlying thyroid disorders. Besides viral factors, the human leukocyte antigen (HLA) may be an independent risk factor. METHODS: We evaluated fifteen patients with HCV chronic hepatitis during a period of 40 months. At the enrollment, all the patients were negative for thyroid disorders, excluding one patient with...
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