Article
Hyper-IgM, neutropenia, mild infections and low response to polyclonal stimulation: hyper-IgM syndrome or common variable immunodeficiency?
International journal of immunopathology and pharmacology - 1 Jan 2000
Rosado M M, Picchianti Diamanti A, Cascioli S, Ceccarelli S, Caporuscio S, D'Amelio R, Carsetti R, Lagana B
Abstract excerpt
A young woman presenting respiratory infections, polyarthritis, severe neutropenia, and increased serum IgM was treated with intravenous immunoglobulin (IVIG) with good clinical and laboratory outcome followed by a loss of efficacy. The increased serum IgM associated to recurrent infections and autoimmune manifestations suggested the diagnosis of a hyper-IgM syndrome (HIGMs). The frequency of peripheral T cells,...
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