Long-term study of a female hyper-IgM immunodeficiency.

doi:10.1159/000019136

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Article

Long-term study of a female hyper-IgM immunodeficiency.

Experimental and clinical immunogenetics - 1 Jan 2000

Kaneko H, Fukao T, Inoue R, Kasahara K, Matsui E, Kondo N

Abstract excerpt

Hyper-IgM immunodeficiency (HIM) is an immunological disorder characterized by normal or elevated serum IgM levels, and reduced serum IgG and IgA levels, due to the disruption of immunoglobulin class switching in B cells. X-linked hyper-IgM is caused by the defective expression of the CD40 ligand...

Topics

Adolescent
Amino Acid Sequence
B-Lymphocytes
Base Sequence
CD40 Antigens
CD40 Ligand
Complementarity Determining Regions
Female
Flow Cytometry
Humans
Immunoglobulin G
Immunoglobulin Heavy Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin M

Immunologic Deficiency Syndromes

Longitudinal Studies

Molecular Sequence Data

Mutation

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 11096255
DOI: 10.1159/000019136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11096255-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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