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Article

Genetic Analysis of Patients with Two Different Types of Hyper IgM Syndrome.

Immunological investigations - 1 Oct 2018

Alizadeh Zahra, Mazinani Marzieh, Houshmand Masoud, Shakerian Leila, Nourizadeh Maryam, Pourpak Zahra, Fazlollahi Mohammad Reza

Abstract excerpt

BACKGROUND: Hyper IgM Syndrome (HIGM) is a rare primary immunodeficiency in which impairment of class switching recombination (CSR) and somatic hyper-mutation (SHM) leads to recurrent infections. OBJECTIVES: The aim of this study is to report the clinical and genetic features of six Iranian HIGM patients. METHODS: Six patients, who suspected to have HIGM based on two clinical findings, including recurrent...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30081731
DOI: 10.1080/08820139.2018.1493052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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