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Article

Clinical and laboratory findings in hyper-IgM syndrome with novel CD40L and AICDA mutations.

Journal of clinical immunology - 1 Nov 2009

Aghamohammadi Asghar, Parvaneh Nima, Rezaei Nima, Moazzami Kasra, Kashef Sara, Abolhassani Hassan, Imanzadeh Amir, Mohammadi Javad, Hammarström Lennart

Abstract excerpt

BACKGROUND: Hyper-immunoglobulin M (HIGM) syndromes are a heterogeneous group of primary immunodeficiency disorders, characterized by recurrent infections associated with decreased serum levels of immunoglobulin G (IgG) and IgA and normal to increased serum levels of IgM. These patients have immunoglobulin class switch recombination defects, caused by mutations in several genes. METHODS: In order to investigate...

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Topics

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Share to AICDA (Activation-Induced Cytidine Deaminase)
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19575287
DOI: 10.1007/s10875-009-9315-7

Genes

AICDA
UNG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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