Article
Human complement factor 3 polymorphism determination by capillary electrophoresis of serum.
Electrophoresis - 1 Feb 2012
De Witte Evy, Speeckaert Marijn M, Van De Moortel Lot, Lecocq Elke, Delanghe Joris R
Abstract excerpt
Variability of complement factor 3 (C3) mobility in serum protein electrophoresis was investigated. We found that the migration time of C3 can be reproducibly determined (beween-run CV=0.76%) using clinical capillary electrophoresis (CE) equipment (the Capillarys™ 2 system, Sebia). Moreover, we found a significant difference (p<0.001) in migration times of the major C3 phenotypes FF (fast-fast), FS (fast-slow)...
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