Article
Genetic predisposition of the severity of joint destruction in rheumatoid arthritis: a population-based study.
Annals of the rheumatic diseases - 1 May 2012
Knevel Rachel, Gröndal Gerður, Huizinga Tom W J, Visser A Willemien, Jónsson Helgi, Víkingsson Arnór, Geirsson Arni Jón, Steinsson Kristján, van der Helm-van Mil Annette H M
Abstract excerpt
BACKGROUND: The susceptibility to rheumatoid arthritis (RA) is partly heritable, but whether the severity of RA is also influenced by genetics has not been determined. The evaluation of the heritability of the severity of RA is basic to further studies on genetic factors. A study was undertaken to determine whether joint destruction is heritable. METHODS: Iceland has an unique comprehensive genealogy database...
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