Article
Wnt/planar cell polarity signaling in the regulation of convergent extension movements during Xenopus gastrulation.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Kim Gun-Hwa, Park Edmond Changkyun, Han Jin-Kwan
Abstract excerpt
The Wnt/planar cell polarity (PCP) signaling pathway plays a critical role in wing, eye, neural tube defects, and sensory bristle development of Drosophila and vertebrate development. Recently, the Wnt/PCP pathway has been known to regulate convergent extension (CE) movements that are essential for establishing the three germ layers and body axis during early vertebrate development. Here, we describe detailed...
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