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Article

Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements.

EMBO reports - 1 May 2005

Jopling Chris, den Hertog Jeroen

Abstract excerpt

Convergent extension (CE) cell movements during gastrulation mediate extension of the anterior-posterior body axis of vertebrate embryos. Non-canonical Wnt5 and Wnt11 signalling is essential for normal CE movements in vertebrate gastrulation. Here, we show that morpholino (MO)-mediated double knock-down of the Fyn and Yes tyrosine kinases in zebrafish embryos impaired normal CE cell movements, resembling the...

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Identifiers

PMID: 15815683
DOI: 10.1038/sj.embor.7400386
PMCID: PMC1299299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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